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The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice

The development of the brain tissue damage in ischemic stroke is composed of an immediate component followed by an inflammatory response with secondary tissue damage after reperfusion. Fisetin, a flavonoid, has multiple biological effects, including neuroprotective and antiinflammatory properties. W...

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Detalhes bibliográficos
Main Authors: Gelderblom, Mathias, Leypoldt, Frank, Lewerenz, Jan, Birkenmayer, Gabriel, Orozco, Denise, Ludewig, Peter, Thundyil, John, Arumugam, Thiruma V, Gerloff, Christian, Tolosa, Eva, Maher, Pamela, Magnus, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345911/
https://ncbi.nlm.nih.gov/pubmed/22234339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.189
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