Deficiency in Serine Protease Inhibitor Neuroserpin Exacerbates Ischemic Brain Injury by Increased Postischemic Inflammation

The only approved pharmacological treatment for ischemic stroke is intravenous administration of plasminogen activator (tPA) to re-canalize the occluded cerebral vessel. Not only reperfusion but also tPA itself can induce an inflammatory response. Microglia are the innate immune cells of the central...

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Detalhes bibliográficos
Main Authors: Gelderblom, Mathias, Neumann, Melanie, Ludewig, Peter, Bernreuther, Christian, Krasemann, Susanne, Arunachalam, Priyadharshini, Gerloff, Christian, Glatzel, Markus, Magnus, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643909/
https://ncbi.nlm.nih.gov/pubmed/23658802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063118
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