Microglial cell activation is a source of metalloproteinase generation during hemorrhagic transformation

Hemorrhage and edema accompany evolving brain tissue injury after ischemic stroke. In patients, these events have been associated with metalloproteinase (MMP)-9 in plasma. Both the causes and cellular sources of MMP-9 generation in this setting have not been defined. MMP-2 and MMP-9 in nonhuman prim...

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Main Authors: del Zoppo, Gregory J, Frankowski, Harald, Gu, Yu-Huan, Osada, Takashi, Kanazawa, Masato, Milner, Richard, Wang, Xiaoyun, Hosomi, Naohisa, Mabuchi, Takuma, Koziol, James A
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345906/
https://ncbi.nlm.nih.gov/pubmed/22354151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.11
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