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Inhibition of IgE-mediated Secretion from Human Basophils with a Highly Selective Bruton’s Tyrosine Kinase, Btk, Inhibitor
The study of receptor-mediated signaling in human basophils is often limited by the availability of selective pharmacological agents. The early signaling reaction mediated by FcεRI aggregation is thought to require the activity of Bruton’s tyrosine kinase (btk), an enzyme that has been identified as...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345890/ https://ncbi.nlm.nih.gov/pubmed/21238622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2010.12.018 |
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