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Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis

Cucurbitacins B and D were among the compounds identified as sensitizers of cancer cells to TRAIL-mediated apoptosis in a high-throughput screen. Therefore a series of cucurbitacins was further investigated for TRAIL sensitization and possible mechanisms of action. A total of six cucurbitacins promo...

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Hlavní autoři: Henrich, Curtis J., Thomas, Cheryl L., Brooks, Alan D., Booth, Nancy Lynn, Lowery, Evan M., Pompei, Richard J., McMahon, James B., Sayers, Thomas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345813/
https://ncbi.nlm.nih.gov/pubmed/21928090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-011-0652-7
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