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A cell-based high-throughput screen to identify synergistic TRAIL sensitizers
We have developed a high-throughput screen (HTS) to search for novel molecules that can synergize with TRAIL, thus promoting apoptosis of ACHN renal tumor cells in a combinatorial fashion. The HTS detects synthetic compounds and pure natural products that can pre-sensitize the cancer cells to TRAIL-...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3168559/ https://ncbi.nlm.nih.gov/pubmed/19089423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0637-8 |
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