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Downregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient mice

Several genetic defects of the nucleotide excision repair (NER) pathway, including deficiency of the Excision Repair Cross-Complementing rodent repair deficiency, complementation group 1 (ERCC1), result in pre-mature aging, impaired growth, microcephaly and delayed development of the cerebellum. The...

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Autors principals: Smith, Scott C., Robinson, Andria R., Niedernhofer, Laura J., Hetman, Michal
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345809/
https://ncbi.nlm.nih.gov/pubmed/22245387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.12.036
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