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A conserved DNA structural control element modulates transcription of a mammalian gene.

The mammalian dihydrofolate reductase (DHFR) gene promoters contain several conserved sequence elements which bind protein, and yet there are other conserved DNA sequences that do not footprint. We report here that mutation of one of these conserved non-footprinting regions increases transcription f...

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Dettagli Bibliografici
Autori principali: Pierce, A J, Jambou, R C, Jensen, D E, Azizkhan, J C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC334574/
https://ncbi.nlm.nih.gov/pubmed/1480478
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