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A conserved DNA structural control element modulates transcription of a mammalian gene.

The mammalian dihydrofolate reductase (DHFR) gene promoters contain several conserved sequence elements which bind protein, and yet there are other conserved DNA sequences that do not footprint. We report here that mutation of one of these conserved non-footprinting regions increases transcription f...

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Detalhes bibliográficos
Main Authors: Pierce, A J, Jambou, R C, Jensen, D E, Azizkhan, J C
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC334574/
https://ncbi.nlm.nih.gov/pubmed/1480478
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