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Iron Accumulation and Neurotoxicity in Cortical Cultures Treated with Holotransferrin
Nonheme iron accumulates in CNS tissue after ischemic and hemorrhagic insults, and may contribute to cell loss. The source of this iron has not been precisely defined. After blood-brain barrier disruption, CNS cells may be exposed to plasma concentrations of transferrin-bound iron (TBI), which excee...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345563/ https://ncbi.nlm.nih.gov/pubmed/21939754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.08.021 |
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