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Minocycline Attenuates Iron Neurotoxicity in Cortical Cell Cultures

Iron neurotoxicity may contribute to the pathogenesis of intracerebral hemorrhage (ICH). The tetracycline derivative minocycline is protective in ICH models, due putatively to inhibition of microglial activation. Although minocycline also chelates iron, its effect on iron neurotoxicity has not been...

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Detalhes bibliográficos
Main Authors: Chen-Roetling, Jing, Chen, Lifen, Regan, Raymond F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782944/
https://ncbi.nlm.nih.gov/pubmed/19523448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.06.026
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