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Therapeutic targeting of cancer cell metabolism

In 1927, Otto Warburg and coworkers reported the increased uptake of glucose and production of lactate by tumors in vivo as compared with normal tissues. This phenomenon, now known as the Warburg effect, was recapitulated in vitro with cancer tissue slices exhibiting excessive lactate production eve...

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Bibliografiske detaljer
Main Authors: Dang, Chi V., Hamaker, Max, Sun, Peng, Le, Anne, Gao, Ping
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345191/
https://ncbi.nlm.nih.gov/pubmed/21301795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-011-0730-x
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