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Therapeutic targeting of cancer cell metabolism
In 1927, Otto Warburg and coworkers reported the increased uptake of glucose and production of lactate by tumors in vivo as compared with normal tissues. This phenomenon, now known as the Warburg effect, was recapitulated in vitro with cancer tissue slices exhibiting excessive lactate production eve...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345191/ https://ncbi.nlm.nih.gov/pubmed/21301795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-011-0730-x |
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