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Selective destruction of abnormal proteins by ubiquitin-mediated protein quality control degradation

Misfolded proteins are continuously produced in the cell and present an escalating detriment to cellular physiology if not managed effectively. As such, all organisms have evolved mechanisms to address misfolded proteins. One primary way eukaryotic cells handle the complication of misfolded proteins...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Fredrickson, Eric K., Gardner, Richard G.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345107/
https://ncbi.nlm.nih.gov/pubmed/22245831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.12.006
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