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Selective destruction of abnormal proteins by ubiquitin-mediated protein quality control degradation
Misfolded proteins are continuously produced in the cell and present an escalating detriment to cellular physiology if not managed effectively. As such, all organisms have evolved mechanisms to address misfolded proteins. One primary way eukaryotic cells handle the complication of misfolded proteins...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345107/ https://ncbi.nlm.nih.gov/pubmed/22245831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.12.006 |
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