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Genetic variation at an YY-1 response site regulates the transcription of cyclin-dependent kinase inhibitor p18(INK4C) transcript in lupus-prone mice
We have previously shown that a novel −74 C to T mutation in the promoter of the cyclin-dependent kinase inhibitor p18 gene was associated with a reduced p18 expression in B cells from mice carrying the Sle2c1 lupus susceptibility locus. To determine the function of the −74 C/T SNP, we have characte...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345103/ https://ncbi.nlm.nih.gov/pubmed/22504641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101992 |
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