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Sphingosine analog AAL-R increases TLR7-mediated dendritic cell responses via p38 and type I IFN signaling pathways
Sphingosine analogs display immunosuppressive activities and thus have therapeutic potential in the treatment of autoimmune diseases. In this study, we investigated the effects of the sphingosine analog AAL-R (FTY720 derivative) on dendritic cell (DC) response upon TLR stimulation. Unlike its known...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345087/ https://ncbi.nlm.nih.gov/pubmed/22490865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102754 |
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