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Hemagglutinin of Influenza A Virus Antagonizes Type I Interferon (IFN) Responses by Inducing Degradation of Type I IFN Receptor 1

Influenza A virus (IAV) employs diverse strategies to circumvent type I interferon (IFN) responses, particularly by inhibiting the synthesis of type I IFNs. However, it is poorly understood if and how IAV regulates the type I IFN receptor (IFNAR)-mediated signaling mode. In this study, we demonstrat...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Xia, Chuan, Vijayan, Madhuvanthi, Pritzl, Curtis J., Fuchs, Serge Y., McDermott, Adrian B., Hahm, Bumsuk
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810695/
https://ncbi.nlm.nih.gov/pubmed/26676772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02749-15
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