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Towards mimicking short linear peptide motifs: identification of new mixed α,β-peptidomimetic ligands for SLAM-Associated Protein (SAP) by confocal on-bead screening

An array of chemical modifications have recently emerged, designed to improve the stability of natural peptides that inherently suffer from short in vivo half-lives, thereby preventing their use as therapeutics. The resultant peptidomimetics resemble native peptides; however, they contain synthetic...

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Bibliografiske detaljer
Main Authors: Hintersteiner, Martin, Knox, Andrew J., Mudd, Gemma, Auer, Manfred
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345037/
https://ncbi.nlm.nih.gov/pubmed/23284589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-011-0071-9
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