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Identification of the molecular mechanisms underlying the cytotoxic action of a potent platinum metallointercalator
Platinum-based DNA metallointercalators are structurally different from the covalent DNA binders such as cisplatin and its derivatives but have potent in vitro activity in cancer cell lines. However, limited understanding of their molecular mechanisms of cytotoxic action greatly hinders their furthe...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345036/ https://ncbi.nlm.nih.gov/pubmed/23226166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-011-0070-x |
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