The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia

Pancreatic cancer is an almost uniformly lethal disease, characterized by late diagnosis, early metastasis, resistance to chemotherapy, and early mutation of the Kras oncogene. Here we show that the receptor for advanced glycation endproducts (RAGE) is required for the activation of interleukin 6 (I...

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Detalhes bibliográficos
Main Authors: Kang, Rui, Loux, Tara, Tang, Daolin, Schapiro, Nicole E., Vernon, Philip, Livesey, Kristen M., Krasinskas, Alyssa, Lotze, Michael T., Zeh, Herbert J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345001/
https://ncbi.nlm.nih.gov/pubmed/22509024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113865109
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