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The receptor for advanced glycation end-products promotes pancreatic carcinogenesis and accumulation of myeloid-derived suppressor cells

Pancreatic ductal adenocarcinoma (PDA) has an aggressive natural history and is resistant to therapy. The receptor for advanced glycation end-products (RAGE) is a pattern recognition receptor for many damage associated molecular pattern (DAMP) molecules. RAGE is overexpressed in both human and murin...

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Detalhes bibliográficos
Main Authors: Vernon, Philip J., Loux, Tara J., Schapiro, Nicole E., Kang, Rui, Muthuswamy, Ravi, Kalinski, Pawel, Tang, Daolin, Lotze, Michael T., Zeh, Herbert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044918/
https://ncbi.nlm.nih.gov/pubmed/23269246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201151
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