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Differences in unwinding of supercoiled DNA induced by the two enantiomers of anti-benzo[a]pyrene diol epoxide.

The unwinding of supercoiled phi X174 RFI DNA induced by the tumorigenic (+) and non-tumorigenic (-) enantiomers of trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE) has been investigated by agarose slab-gel and ethidium titration tube gel electrophoresis. The differences...

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Autors principals: Xu, R, Birke, S, Carberry, S E, Geacintov, N E, Swenberg, C E, Harvey, R G
Format: Artigo
Idioma:Inglês
Publicat: 1992
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC334500/
https://ncbi.nlm.nih.gov/pubmed/1475180
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