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Bacteriophage T4 polynucleotide kinase triggers degradation of mRNAs

The bacteriophage T4-encoded RegB endoribonuclease is produced during the early stage of phage development and targets mostly (but not exclusively) the Shine–Dalgarno sequences of early genes. In this work, we show that the degradation of RegB-cleaved mRNAs depends on a functional T4 polynucleotide...

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Bibliografische gegevens
Hoofdauteurs: Durand, Sylvain, Richard, Graziella, Bontems, François, Uzan, Marc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344967/
https://ncbi.nlm.nih.gov/pubmed/22499790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119802109
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