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Structural Analyses of the Slm1-PH Domain Demonstrate Ligand Binding in the Non-Canonical Site
BACKGROUND: Pleckstrin homology (PH) domains are common membrane-targeting modules and their best characterized ligands are a set of important signaling lipids that include phosphatidylinositol phosphates (PtdInsPs). PH domains recognize PtdInsPs through two distinct mechanisms that use different bi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3344901/ https://ncbi.nlm.nih.gov/pubmed/22574179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036526 |
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