The fbpA/sapM Double Knock Out Strain of Mycobacterium tuberculosis Is Highly Attenuated and Immunogenic in Macrophages

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is the leading cause of death due to bacterial infections in mankind, and BCG, an attenuated strain of Mycobacterium bovis, is an approved vaccine. BCG sequesters in immature phagosomes of antigen presenting cells (APCs), which do not fu...

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Bibliografische gegevens
Hoofdauteurs: Saikolappan, Sankaralingam, Estrella, Jaymie, Sasindran, Smitha J., Khan, Arshad, Armitige, Lisa Y., Jagannath, Chinnaswamy, Dhandayuthapani, Subramanian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344844/
https://ncbi.nlm.nih.gov/pubmed/22574140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036198
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