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Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation

To assess whether heterozygosity of the donor cell genome was a general parameter crucial for long-term survival of cloned animals, we tested the ability of embryonic stem (ES) cells with either an inbred or F(1) genetic background to generate cloned mice by nuclear transfer. Most clones derived fro...

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Detalhes bibliográficos
Main Authors: Eggan, Kevin, Akutsu, Hidenori, Loring, Janet, Jackson-Grusby, Laurie, Klemm, Martina, Rideout, William M., Yanagimachi, Ryuzo, Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC33447/
https://ncbi.nlm.nih.gov/pubmed/11331774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101118898
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