Genetic effects of oxidative DNA damage: comparative mutagenesis of 7,8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine in Escherichia coli.

A single 7,8-dihydro-8-oxoguanine (G8-OXO; 8-hydroxyguanine) adduct in the lacZ alpha gene of bacteriophage M13 DNA induces a targeted G-->T transversion after replication in Escherichia coli (Biochemistry, 29, 7024-7031 (1990)). This mutation is thought to be due to the facile formation during DNA...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Wood, M L, Esteve, A, Morningstar, M L, Kuziemko, G M, Essigmann, J M
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1992
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1461734/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.22.6023
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