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Analysis of the autonomous replication behavior in human cells of the dihydrofolate reductase putative chromosomal origin of replication.

Chinese hamster genomic DNA sequences from the region downstream of the dihydrofolate reductase (DHFR) gene reported to contain a chromosomal origin of bidirectional DNA replication (OBR-1) were tested for their ability to support autonomous DNA replication in human cells. A 13.3 kilobase fragment c...

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Autores principales: Caddle, M S, Calos, M P
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC334462/
https://ncbi.nlm.nih.gov/pubmed/1461730
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