Загрузка...

Identification of Important Chemical Features of 11β-Hydroxysteroid Dehydrogenase Type1 Inhibitors: Application of Ligand Based Virtual Screening and Density Functional Theory

11β-Hydroxysteroid dehydrogenase type1 (11βHSD1) regulates the conversion from inactive cortisone to active cortisol. Increased cortisol results in diabetes, hence quelling the activity of 11βHSD1 has been thought of as an effective approach for the treatment of diabetes. Quantitative hypotheses wer...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Sakkiah, Sugunadevi, Meganathan, Chandrasekaran, Sohn, Young-Sik, Namadevan, Sundaraganesan, Lee, Keun Woo
Формат: Artigo
Язык:Inglês
Опубликовано: Molecular Diversity Preservation International (MDPI) 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344271/
https://ncbi.nlm.nih.gov/pubmed/22606035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13045138
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!