A ribozyme with DNA in the hybridising arms displays enhanced cleavage ability.
Hammerhead ribozymes cleave RNA substrates containing the UX sequence, where X = U, C or A, embedded within sequences which are complementary to the hybridising 'arms' of the ribozyme. In this study we have replaced the RNA in the hybridising arms of the ribozyme with DNA, and the resulting ribozyme...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1992
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| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1280808/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.21.5737 |
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