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Heme Cytotoxicity and the Pathogenesis of Immune-Mediated Inflammatory Diseases

Heme, iron (Fe) protoporphyrin IX, functions as a prosthetic group in a range of hemoproteins essential to support life under aerobic conditions. The Fe contained within the prosthetic heme groups of these hemoproteins can catalyze the production of reactive oxygen species. Presumably for this reaso...

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Detalhes bibliográficos
Main Authors: Larsen, Rasmus, Gouveia, Zélia, Soares, Miguel P., Gozzelino, Raffaella
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343703/
https://ncbi.nlm.nih.gov/pubmed/22586395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00077
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