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α-synuclein, LRRK2 and their interplay in Parkinson’s disease
Of the various genetic factors contributing to the pathogenesis of Parkinson’s disease (PD), only mutations in α-synuclein (α-syn) and LRRK2 genes cause clinical and neuropathological phenotypes closely resembling the sporadic cases. Therefore, studying the pathophysiological functions of these two...
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Autori principali: | , , |
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Natura: | Artigo |
Lingua: | Inglês |
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2012
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343692/ https://ncbi.nlm.nih.gov/pubmed/22563296 |
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