Akt is negatively regulated by the MULAN E3 ligase

The serine/threonine kinase Akt functions in multiple cellular processes, including cell survival and tumor development. Studies of the mechanisms that negatively regulate Akt have focused on dephosphorylation-mediated inactivation. In this study, we identified a negative regulator of Akt, MULAN, wh...

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Detalhes bibliográficos
Main Authors: Bae, Seunghee, Kim, Sun-Yong, Jung, Jin Hyuk, Yoon, Yeongmin, Cha, Hwa Jun, Lee, Hyunjin, Kim, Karam, Kim, Jongran, An, In-Sook, Kim, Jongdoo, Um, Hong-Duck, Park, In-Chul, Lee, Su-Jae, Nam, Seon Young, Jin, Young-Woo, Lee, Jae Ho, An, Sungkwan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343661/
https://ncbi.nlm.nih.gov/pubmed/22410793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.38
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