MRG-1 is required for genomic integrity in Caenorhabditis elegans germ cells

During meiotic cell division, proper chromosome synapsis and accurate repair of DNA double strand breaks (DSBs) are required to maintain genomic integrity, loss of which leads to apoptosis or meiotic defects. The mechanisms underlying meiotic chromosome synapsis, DSB repair and apoptosis are not ful...

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Библиографические подробности
Главные авторы: Xu, Jing, Sun, Xiaojuan, Jing, Yudong, Wang, Mo, Liu, Kai, Jian, Youli, Yang, Mei, Cheng, Zhukuan, Yang, Chonglin
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2012
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343660/
https://ncbi.nlm.nih.gov/pubmed/22212480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.2
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