MRG-1 is required for genomic integrity in Caenorhabditis elegans germ cells

During meiotic cell division, proper chromosome synapsis and accurate repair of DNA double strand breaks (DSBs) are required to maintain genomic integrity, loss of which leads to apoptosis or meiotic defects. The mechanisms underlying meiotic chromosome synapsis, DSB repair and apoptosis are not ful...

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Detalhes bibliográficos
Main Authors: Xu, Jing, Sun, Xiaojuan, Jing, Yudong, Wang, Mo, Liu, Kai, Jian, Youli, Yang, Mei, Cheng, Zhukuan, Yang, Chonglin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343660/
https://ncbi.nlm.nih.gov/pubmed/22212480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.2
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