Tie1 deficiency induces endothelial–mesenchymal transition

Endothelial–mesenchymal transition (EndMT) has a significant role in embryonic heart formation and in various pathologies. However, the molecular mechanisms that regulate EndMT induction remain to be elucidated. We show that suppression of receptor tyrosine kinase Tie1 but not Tie2 induces human end...

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Bibliografiska uppgifter
Huvudupphovsmän: Garcia, Julie, Sandi, Maria José, Cordelier, Pierre, Binétruy, Bernard, Pouysségur, Jacques, Iovanna, Juan Lucio, Tournaire, Roselyne
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2012
Ämnen:
Scientific Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343349/
https://ncbi.nlm.nih.gov/pubmed/22421998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.29
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