Tie1 deficiency induces endothelial–mesenchymal transition

Endothelial–mesenchymal transition (EndMT) has a significant role in embryonic heart formation and in various pathologies. However, the molecular mechanisms that regulate EndMT induction remain to be elucidated. We show that suppression of receptor tyrosine kinase Tie1 but not Tie2 induces human end...

Full description

Saved in:
Bibliographic Details
Main Authors: Garcia, Julie, Sandi, Maria José, Cordelier, Pierre, Binétruy, Bernard, Pouysségur, Jacques, Iovanna, Juan Lucio, Tournaire, Roselyne
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
Subjects:
Scientific Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343349/
https://ncbi.nlm.nih.gov/pubmed/22421998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.29
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items