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Tie1 deficiency induces endothelial–mesenchymal transition

Endothelial–mesenchymal transition (EndMT) has a significant role in embryonic heart formation and in various pathologies. However, the molecular mechanisms that regulate EndMT induction remain to be elucidated. We show that suppression of receptor tyrosine kinase Tie1 but not Tie2 induces human end...

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Detalhes bibliográficos
Main Authors: Garcia, Julie, Sandi, Maria José, Cordelier, Pierre, Binétruy, Bernard, Pouysségur, Jacques, Iovanna, Juan Lucio, Tournaire, Roselyne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343349/
https://ncbi.nlm.nih.gov/pubmed/22421998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.29
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