Ebola virus entry requires the host-programmed recognition of an intracellular receptor

Ebola and Marburg filoviruses cause deadly outbreaks of haemorrhagic fever. Despite considerable efforts, no essential cellular receptors for filovirus entry have been identified. We showed previously that Niemann-Pick C1 (NPC1), a lysosomal cholesterol transporter, is required for filovirus entry....

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Miller, Emily Happy, Obernosterer, Gregor, Raaben, Matthijs, Herbert, Andrew S, Deffieu, Maika S, Krishnan, Anuja, Ndungo, Esther, Sandesara, Rohini G, Carette, Jan E, Kuehne, Ana I, Ruthel, Gordon, Pfeffer, Suzanne R, Dye, John M, Whelan, Sean P, Brummelkamp, Thijn R, Chandran, Kartik
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343336/
https://ncbi.nlm.nih.gov/pubmed/22395071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.53
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky