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Claudin-14 regulates renal Ca(++) transport in response to CaSR signalling via a novel microRNA pathway
The paracellular claudin channel of the thick ascending limb (TAL) of Henle is critical for Ca(++) reabsorption in the kidney. Genome-wide association studies (GWASs) have identified claudin-14 associated with hypercalciuric nephrolithiasis. Here, we show that claudin-14 promoter activity and transc...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343334/ https://ncbi.nlm.nih.gov/pubmed/22373575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.49 |
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