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Claudin-14 regulates renal Ca(++) transport in response to CaSR signalling via a novel microRNA pathway

The paracellular claudin channel of the thick ascending limb (TAL) of Henle is critical for Ca(++) reabsorption in the kidney. Genome-wide association studies (GWASs) have identified claudin-14 associated with hypercalciuric nephrolithiasis. Here, we show that claudin-14 promoter activity and transc...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gong, Yongfeng, Renigunta, Vijayaram, Himmerkus, Nina, Zhang, Jiaqi, Renigunta, Aparna, Bleich, Markus, Hou, Jianghui
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343334/
https://ncbi.nlm.nih.gov/pubmed/22373575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.49
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