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Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing.
We have used a combination of highly specific protein phosphatase inhibitors and purified mammalian protein phosphatases to show that at least two separate Ser/Thr protein phosphatase activities are required for pre-mRNA splicing, but not for spliceosome assembly. Okadaic acid, tautomycin, and micro...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1992
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334330/ https://ncbi.nlm.nih.gov/pubmed/1331983 |
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