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Role of expression site switching in the development of resistance to human Trypanosome Lytic Factor-1 in Trypanosoma brucei brucei

Human high-density lipoproteins (HDLs) play an important role in human innate immunity to infection by African trypanosomes with a minor subclass, Trypanosome Lytic Factor-1 (TLF-1), displaying highly selective cytotoxicity to the veterinary pathogen Trypanosoma brucei brucei but not against the hum...

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Autori principali: Kieft, Rudo, Stephens, Natalie A., Capewell, Paul, MacLeod, Annette, Hajduk, Stephen L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier/North-Holland Biomedical Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343262/
https://ncbi.nlm.nih.gov/pubmed/22226682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2011.12.004
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