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Immunological Tolerance to Muscle Autoantigens Involves Peripheral Deletion of Autoreactive CD8(+) T Cells
Muscle potentially represents the most abundant source of autoantigens of the body and can be targeted by a variety of severe autoimmune diseases. Yet, the mechanisms of immunological tolerance toward muscle autoantigens remain mostly unknown. We investigated this issue in transgenic SM-Ova mice tha...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343038/ https://ncbi.nlm.nih.gov/pubmed/22570714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036444 |
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