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The role of peripheral T-cell deletion in transplantation tolerance.
The apoptotic deletion of thymocytes that express self-reactive antigen receptors is the basis of central (thymic) self-tolerance. However, it is clear that some autoreactive T cells escape deletion in the thymus and exist as mature lymphocytes in the periphery. Therefore, peripheral mechanisms of t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1088449/ https://ncbi.nlm.nih.gov/pubmed/11375065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2001.0845 |
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