Age-Dependent TLR3 Expression of the Intestinal Epithelium Contributes to Rotavirus Susceptibility

Rotavirus is a major cause of diarrhea worldwide and exhibits a pronounced small intestinal epithelial cell (IEC) tropism. Both human infants and neonatal mice are highly susceptible, whereas adult individuals remain asymptomatic and shed only low numbers of viral particles. Here we investigated age...

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Detalhes bibliográficos
Main Authors: Pott, Johanna, Stockinger, Silvia, Torow, Natalia, Smoczek, Anna, Lindner, Cornelia, McInerney, Gerald, Bäckhed, Fredrik, Baumann, Ulrich, Pabst, Oliver, Bleich, André, Hornef, Mathias W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343008/
https://ncbi.nlm.nih.gov/pubmed/22570612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002670
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