Detection of BRAF mutations in patients with hairy cell leukemia and related lymphoproliferative disorders

Hairy cell leukemia has been shown to be strongly associated with the BRAF V600E mutation. We screened 59 unenriched archived bone marrow aspirate and peripheral blood samples from 51 patients with hairy cell leukemia using high resolution melting analysis and confirmatory Sanger sequencing. The BRA...

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Detalhes bibliográficos
Main Authors: Blombery, Piers A., Wong, Stephen Q., Hewitt, Chelsee A., Dobrovic, Alexander, Maxwell, Ellen L., Juneja, Surender, Grigoriadis, George, Westerman, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342983/
https://ncbi.nlm.nih.gov/pubmed/22133769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.054874
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