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Minocycline markedly reduces acute visceral nociception via inhibiting neuronal ERK phosphorylation

BACKGROUND: Minocycline prevents the development of neuropathic and inflammatory pain by inhibiting microglial activation and postsynaptic currents. But, how minocycline obviates acute visceral pain is unclear. The present study investigated whether minocycline had an any antinociceptive effect on a...

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Main Authors: Cho, Ik-Hyun, Lee, Min Jung, Jang, Minhee, Gwak, Nam Gil, Lee, Ka Yeon, Jung, Hyuk-Sang
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342906/
https://ncbi.nlm.nih.gov/pubmed/22364340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-13
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