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Minocycline markedly reduces acute visceral nociception via inhibiting neuronal ERK phosphorylation

BACKGROUND: Minocycline prevents the development of neuropathic and inflammatory pain by inhibiting microglial activation and postsynaptic currents. But, how minocycline obviates acute visceral pain is unclear. The present study investigated whether minocycline had an any antinociceptive effect on a...

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Hlavní autoři: Cho, Ik-Hyun, Lee, Min Jung, Jang, Minhee, Gwak, Nam Gil, Lee, Ka Yeon, Jung, Hyuk-Sang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342906/
https://ncbi.nlm.nih.gov/pubmed/22364340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-13
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