ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia

Asparaginase is a standard and critical component in the therapy of childhood acute lymphoblastic leukemia. Asparagine synthetase (ASNS) and the basic region leucine zipper activating transcription factor 5 (ATF5) and arginosuccinate synthase 1 (ASS1) have been shown to mediate the antileukemic effe...

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Autors principals: Rousseau, Julie, Gagné, Vincent, Labuda, Malgorzata, Beaubois, Cyrielle, Sinnett, Daniel, Laverdière, Caroline, Moghrabi, Albert, Sallan, Stephen E., Silverman, Lewis B., Neuberg, Donna, Kutok, Jeffery L., Krajinovic, Maja
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
Matèries:
Clinical Trials and Observations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342855/
https://ncbi.nlm.nih.gov/pubmed/21972289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-355560
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